Ipenija 30 Awọn Ẹ̀fọ́
Tẹle gbogbo awọn eya ẹfọ ti o yatọ. Iyatọ, kii ṣe iye, ni o n ṣe awakọ iyatọ microbial — asọtẹlẹ ti o dara julọ fun ikun ti o lagbara.
McDonald et al., 2018 — mSystems (American Gut Project)Ilera ti ara ẹni ti ikun-ọpọlọ
Ikun rẹ n ṣe apẹrẹ ni pẹlẹpẹlẹ irẹlẹ rẹ, ifojusi, ati ọjọ iwaju.
Veliome n yi imọ tuntun ti microbiome pada si iṣe ojoojumọ — 30 irugbin ni ọsẹ kan, ounjẹ ti a ṣe, ati awọn yiyan igbesi aye kekere ti o n gbe igi lori inflammation, agbara, ati irisi ọpọlọ.
Ti a ṣe atilẹyin nipasẹ awọn iwadi 30+ ti a ṣe ayẹwo nipasẹ awọn ẹlẹgbẹ
78 Gut Score
23 plants 8 ferments +4 today
Ohun ti iwadi naa fihan gangan
Ọpọlọpọ awọn agbalagba n jẹ diẹ ẹ sii ju 12 awọn irugbin oriṣiriṣi ni ọsẹ kan. Awọn microbiomes ti o ni ọlọrọ julọ jẹ ti awọn eniyan ti n jẹ 30 tabi diẹ sii.
30+
awọn irugbin oriṣiriṣi fun ọsẹ kan ni ipele oriṣiriṣi ti o ni nkan ṣe pẹlu awọn microbiomes ikun ti o ni ilera julọ (American Gut Project).
60%
ti awọn kalori ninu ounje iwọ-oorun deede wa lati ounjẹ ti a ṣe ilana, asọtẹlẹ ounje ti o lagbara julọ ti iku gbogbo-idi.
95%
ti serotonin ti ara rẹ ni a ṣe ni ikun, ti n fi microbiome si aarin iṣakoso irẹlẹ.
10 ọsẹ
ti ounjẹ ti a ṣe lojoojumọ mu ilọsiwaju microbial pọ si ati dinku 19 awọn protein inflammatory ni idanwo Stanford kan.
Eto pipe fun ikun ilera julọ
Gbogbo ẹya wa lati jẹ ki apakan kan ti iwadi microbiome jẹ ohun ti a le ṣe.
Awọn Ounjẹ Fermented Ojoojumọ
Kefir, yogurt, kimchi, kraut, miso, kombucha, sourdough. Iwọn ti a ko lo pupọ julọ fun iyatọ ikun ati dinku inflammation.
Wastyk et al., 2021 — CellAwọn Imọran Ikun-Ọpọlọ
Ṣe igbasilẹ irọra, ifojusi, oorun, ati ọpọlọ fog. Veliome n ṣe afihan awọn ilana ounje ti o ni ibatan julọ pẹlu bi o ṣe n rilara.
Cryan et al., 2019 — Physiological ReviewsAwọn Ikilọ Ounjẹ Ultra-Processed
Ri UPFs ninu awọn ounje rẹ ṣaaju ki wọn to di ihuwasi. Ti kọ lori iṣiro NOVA ti a lo ninu iwadi ounje.
Monteiro et al., 2019 — Public Health NutritionIye Ikun Rẹ lojoojumọ
Nọmba kan 0-100 ti o ṣe afihan iyatọ ẹfọ, awọn ferments, ẹru UPF, ati igbesi aye. Awọn imudojuiwọn pẹlu gbogbo ounje ti a ti ṣe igbasilẹ.
Ibi ifihan apapọ, ti a fọwọsi lodi si awọn ami PREDICT-2 cohortAtokọ ayẹwo ilera ẹnu
Ikun rẹ bẹrẹ ninu ẹnu rẹ. Flossing ati itọju ahọn dinku awọn bacteria ti o ni nkan ṣe pẹlu inflammation eto ati ewu dementia.
Dominy et al., 2019 — Science AdvancesWindo 12-wakati alẹ
Ijẹun alẹ ti o rọ mu ki iṣan gbigbe ti nlọ — igbi itọju ikun.
Deloose et al., 2012 — Nature Reviews GastroenterologyẸrọ idanwo microbiome ti o yan
Ayẹwo idalẹnu ti a fi ranṣẹ. Akopọ bacteria ti o ni alaye, awọn superfoods ti a ṣe adani, ati itọkasi inflammation — gbogbo wọn ni a ṣepọ sinu iboju iṣakoso rẹ.
16S rRNA + shotgun sequencing, lab-verifiedBawo ni Veliome ṣe n ṣiṣẹ
Iṣẹju marun ni ọjọ kan. Iyipada gidi ni awọn ọsẹ mẹta.
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1. Ṣe adani
Dahun awọn ibeere 11 nipa ounje rẹ, oorun, aapọn, ati awọn aami aisan. Veliome n ṣe afihan profaili microbiome ibẹrẹ rẹ.
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2. Ṣe igbasilẹ
Ya awọn ounje, tẹ awọn ewe, ṣe igbasilẹ awọn ferment. Ohun elo naa n ṣe iṣiro ati mu awọn ilana wa.
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3. Ṣatunṣe
Awọn ifamọra lojoojumọ n fihan ọ iyipada ti o ni agbara julọ fun ibẹrẹ rẹ. Kere, pato, ko si ikẹkọ.
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4. Tẹle awọn abajade
Wo Gut Score rẹ, mood, ati awọn shatti agbara n gbe. Ẹ̀rọ idanwo aṣayan n jinlẹ aworan naa ni gbogbo oṣu mẹfa.
Imọ̀ nípa gbogbo ẹya
Veliome dá lórí ìwádìí microbiome tí a fọwọ́ sí láti ọ̀dọ̀ àwọn ẹlẹ́rìí ní ọdún mẹ́wàá tó kọjá. Gbogbo ẹ̀sùn ní ìjápọ̀ pẹ̀lú orísun àkọ́kọ́.
Iyatọ̀ ọgbin → iyatọ̀ microbial
Ilana American Gut ṣe àyẹ̀wò 11,336 àpẹẹrẹ ikọ̀ àtọ́ka àti rí i pé àwọn ènìyàn tó ń jẹ 30+ ọgbin tó yàtọ̀ síra ni ọ̀sẹ̀ kan ní microbiomes ikọ̀ àtọ́ka tó yàtọ̀ sí i — àti pé iye àjẹsara àtọ́ka wọn kéré jùlọ — ju àwọn tó ń jẹ 10 tàbí kere jù bẹ́ẹ̀ lọ.
McDonald et al., mSystems 2018Àwọn oúnjẹ tí a ti fọ́kàn tán dín iná àtọ́ka kù
Nínú ìdánwò Stanford tó pé ọ̀sẹ̀ mẹ́wàá, àwọn àgbàlagbà tó ní ilera tó fi 6 ìpẹ̀yà oúnjẹ tí a ti fọ́kàn tán kún àdánwò wọn pọ̀ si i, pọ̀ si iyatọ̀ microbial ÀTI dín 19 àwọn ẹ̀dá àtọ́ka, pẹ̀lú IL-6 — tó ní ipa nínú àìlera àtọ́ka.
Wastyk et al., Cell 2021Ẹ̀mí wa nínú ikọ̀ àtọ́ka
Nipa 95% ti serotonin ti ara ni a ṣe ni awọn sẹẹli enterochromaffin ti o wa ni ila inu ikun. Awọn kokoro kan pato (ti o n ṣe spores, pẹlu Clostridium ati Turicibacter) n ṣakoso taara biosynthesis rẹ. Ẹ̀dá vagus n gbe awọn ifiranṣẹ ikun si ọpọlọ ni awọn iṣẹju diẹ.
Yano et al., Cell 2015 · Cryan et al., Physiological Reviews 2019Ounjẹ ti a ti ṣe ilana pupọ (UPF) ati ikun
UPFs dinku oriṣiriṣi microbial, fa ìkànsí, ati kọja itẹlọrun. Wọn ti di ~58% ti awọn kalori ni AMẸRIKA ati 60% ni UK. Gbigba UPF ti o ga julọ ni ibatan ominira pẹlu iku gbogbo-idi ni awọn ẹgbẹ ti o tobi.
Monteiro et al., 2019 · Pagliai et al., 2021Awọn microbes ẹnu n ni ipa lori ọpọlọ
Porphyromonas gingivalis, kokoro ti o wa lẹhin periodontitis àkúnya, ti wa ni idanimọ ninu awọn ohun elo ọpọlọ Alzheimer ati CSF. Fọ ẹnu lojoojumọ ati itọju ahọn dinku ẹru pathogens ẹnu ati ìkànsí eto.
Dominy et al., Science Advances 2019Idahun ti a ṣe adani jẹ otitọ
Iwadi PREDICT-1 (1,098 awọn eniyan ti a ṣe phenotyped jinlẹ) fihan pe awọn idahun glucose, insulin, ati triglyceride lẹhin ounje si awọn ounje kanna yato si ni pataki laarin awọn eniyan — ati pe akopọ microbiome jẹ ọkan ninu awọn asọtẹlẹ to lagbara julọ ti iyatọ yẹn. Iṣeduro ounje gbogbogbo kuna nitori o foju kọ ọ.
Asnicar et al., Nature Medicine 2021Àwọn ìtọ́kasí tí a yàn
- McDonald, D. et al. (2018). American Gut: An Open Platform for Citizen Science Microbiome Research. mSystems, 3(3).
- Wastyk, H. C. et al. (2021). Gut-microbiota-targeted diets modulate human immune status. Cell, 184(16), 4137–4153.
- Cryan, J. F. et al. (2019). The Microbiota-Gut-Brain Axis. Physiological Reviews, 99(4), 1877–2013.
- Monteiro, C. A. et al. (2019). Ultra-processed foods: what they are and how to identify them. Public Health Nutrition, 22(5), 936–941.
- Dominy, S. S. et al. (2019). Porphyromonas gingivalis in Alzheimer's disease brains. Science Advances, 5(1).
- Deloose, E. et al. (2012). The migrating motor complex: control mechanisms and its role in health and disease. Nature Reviews Gastroenterology & Hepatology, 9, 271–285.
- Berding, K. et al. (2023). A specific dietary fibre supplementation improves cognitive performance — an exploratory randomised, placebo-controlled, crossover study. Psychopharmacology.
- Asnicar, F. et al. (2021). Microbiome connections with host metabolism and habitual diet from 1,098 deeply phenotyped individuals. Nature Medicine, 27, 321–332. (PREDICT-1)
- Berding, K. et al. (2021). Diet and the microbiota-gut-brain axis: sowing the seeds of good mental health. Advances in Nutrition, 12(4).
- Sender, R., Fuchs, S., & Milo, R. (2016). Revised estimates for the number of human and bacteria cells in the body. PLoS Biology, 14(8).
- Yano, J. M. et al. (2015). Indigenous bacteria from the gut microbiota regulate host serotonin biosynthesis. Cell, 161(2), 264–276.
- Pase, M. P. et al. (2020). Sleep architecture and the risk of incident dementia in the community. Neurology, 95(5).
- Beilharz, J. E. et al. (2015). Diet-induced cognitive deficits: The role of fat and sugar, potential mechanisms and nutritional interventions. Nutrients, 7(8).
- Sonnenburg, J. L., & Sonnenburg, E. D. (2019). The ancestral and industrialized gut microbiota and implications for human health. Nature Reviews Microbiology, 17, 383–390.
- Valdes, A. M. et al. (2018). Role of the gut microbiota in nutrition and health. BMJ, 361.
Awọn ọmọ ẹgbẹ ti n ri i tẹlẹ
Mi o ni imọran pe oriṣiriṣi ṣe pataki ju iye lọ. Oluttracker 30-ewe tun ṣe gbogbo nkan. Mo lọ lati 8 ewe ni ọsẹ kan si 34 ni awọn ọsẹ mẹta — ati nikẹhin ni pẹlẹpẹlẹ ni 9am.
Shatti ibatan mood-ounje ni bọtini ṣiṣi. Mo da ija ti ikuna ọsan duro ati bẹrẹ si dena rẹ.
Dokita mi ti gastroenterology beere ohun ti mo ti yi pada. Mo fi aworan Gut Score han an. O gba app naa ni ọsan yẹn.
Awọn ibeere ti a beere nigbagbogbo
Ṣe Veliome jẹ ẹrọ iṣoogun tabi irinṣẹ ayẹwo?
Rara. Veliome jẹ app ilera ti a ṣe apẹrẹ lati jẹ ki iwadi microbiome jẹ iṣẹ-ṣiṣe. Ko ṣe ayẹwo, tọju, ṣe iwosan, tabi dena eyikeyi arun. Fun awọn ipo iṣoogun, kan si dokita.
Ṣe mo nilo kit idanwo lati lo app naa?
Rara. Awọn ipele ọfẹ ati ti o ga ṣiṣẹ laisi idanwo ile-iwosan. Kit naa jẹ afikun ti o jẹ aṣayan ti o funni ni profaili bakteeriya ti ara ẹni ati atokọ ounje ti a ṣe adani.
Iru iṣẹ wo ni awọn onimọ-jinlẹ ti o ni ipa lori Veliome?
App naa ni alaye pupọ lati ọdọ Prof. Tim Spector (King's College London / ZOE / PREDICT), Justin Sonnenburg (Stanford), John Cryan (APC Microbiome Ireland), ati ẹgbẹ American Gut Project ti o gbooro. Gbogbo awọn ẹtọ ni asopọ si awọn orisun akọkọ ti a fọwọsi nipasẹ ẹlẹgbẹ.
Bawo ni atilẹyin ede 108 ṣe n ṣiṣẹ?
Mejeeji app ati oju opo wẹẹbu yii ni a tumọ pẹlu lilo awoṣe OpenAI's gpt-4o-mini. Oju opo wẹẹbu naa n ṣe afihan oju-iwe HTML kan fun ede kọọkan fun iṣiro ẹrọ wiwa ni kikun.
Ṣe data mi jẹ ikọkọ?
Bẹẹni. Gbogbo awọn igbasilẹ ounje, awọn iforukọsilẹ irọra, ati awọn metiriki ni a fipamọ sori ẹrọ rẹ nipasẹ aiyipada. Ko si data ti ara ẹni ti o kuro ninu foonu rẹ ayafi ti o ba yan ni kedere lati kopa ninu igbimọ iwadi.
Ṣe Veliome yoo ṣiṣẹ ti mo ba jẹ vegan / keto / Mediterranean?
Bẹẹni. Veliome jẹ alailẹgbẹ si ilana ounje. Ilana 30-plants ati itọsọna ounje ti a fermente mu ilọsiwaju si eyikeyi ara jijẹ.
Bawo ni eyi ṣe yatọ si MyFitnessPal tabi Yuka?
MyFitnessPal n tọpa awọn kalori. Yuka n ṣe iwọn awọn ọja ni awọn ile itaja. Veliome jẹ apẹrẹ pataki ni ayika imọ-jinlẹ microbiome: oriṣiriṣi, ferments, UPF load, ati axis gut-brain — kii ṣe iṣiro kalori.
Nibo ni mo ti le ka awọn iwadi?
Gbogbo kaadi imọ-jinlẹ lori oju-iwe yii ni asopọ si orisun akọkọ rẹ. Atokọ itọkasi kikun wa ni isalẹ apakan Imọ-jinlẹ.
Bẹrẹ irin-ajo microbiome rẹ loni
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