Nchọpụta 30 Ahịa
Soro ụdị osisi dị iche iche niile. Ntụgharị, ọ bụghị ọnụ ọgụgụ, na-eme ka ọdịiche microbial — onye na-eme ka ahụ dịkwuo ike.
McDonald et al., 2018 — mSystems (American Gut Project)Nchekwa ahụ́ na ụbụrụ nke onwe
Afọ gị na-emetụta mmetụta gị, ntị, na ọdịnihu.
Veliome na-eme ka sayensị ọhụrụ nke microbiome bụrụ omume kwa ụbọchị — osisi 30 kwa izu, nri a na-eme ka ọ bụrụ ihe, na nhọrọ ndụ ndị nta nke na-eme ka inflammation, ike, na ụbụrụ fog.
Nkwado site na ọmụmụ 30+ nke ndị otu nyocha
78 Gut Score
23 plants 8 ferments +4 today
Ihe nyocha na-egosi n'ezie
Ọtụtụ ndị okenye na-eri osisi dị iche iche na-erughị 12 kwa izu. Microbiomes kachasị baa ọgaranya bụ nke ndị na-eri osisi 30 ma ọ bụ karịa.
30+
osisi dị iche iche kwa izu bụ oke iche iche nke metụtara microbiomes afọ kachasị mma (American Gut Project).
60%
nke kalori na nri ọdịda anyanwụ bụ sitere na nri a na-eme ka ọ bụrụ ihe, nke bụ onye na-eme ka nri na-akpata ọnwụ n'ozuzu.
95%
nke serotonin nke ahụ gị na-emepụta na afọ, na-eme ka microbiome bụrụ isi nke njikwa mmetụta.
10 izu
nke nri a na-eme ka ọ bụrụ ihe kwa ụbọchị na-abawanye iche iche microbial ma belata 19 proteins na-akpata inflammation na nyocha Stanford.
Usoro zuru ezu maka afọ healthier
Njikọ ọ bụla dị iji mee ka otu akụkụ nke nyocha microbiome bụrụ ihe a na-eme.
Nri Fermented kwa ụbọchị
Kefir, yogurt, kimchi, kraut, miso, kombucha, sourdough. Nke a bụ ihe kachasị adịghị eji eme ihe maka ọdịiche gut na belata inflammation.
Wastyk et al., 2021 — CellNcheta Gut-Brain
Debe mmetụta, ịtụ uche, ụra, na ụjọ ụbụrụ. Veliome na-egosipụta ụdị nri kachasị metụtara otú ị na-eche.
Cryan et al., 2019 — Physiological ReviewsNkwupụta Nri Ultra-Processed
Chọpụta UPFs na nri gị tupu ha abanye n'ọrụ. E wuru gburugburu nkwupụta NOVA eji eme nnyocha nri.
Monteiro et al., 2019 — Public Health NutritionNchịkọta Gut gị kwa ụbọchị
Otu nọmba 0-100 na-egosipụta ọdịiche osisi, ferments, ibu UPF, na ndụmọdụ. Na-emelite na nri ọ bụla edere.
Composite signal, validated against PREDICT-2 cohort markersNdepụta nyocha ahụike ọnụ
Gut gị malitere na ọnụ gị. Iji floss na nlekọta asụsụ na-ebelata nje bacteria metụtara inflammation sistematik na ihe ize ndụ dementia.
Dominy et al., 2019 — Science AdvancesOge 12 awa n'abalị
Nri n'abalị dị nro na-akpọrọ ọrụ motor na-agba ọsọ — ụkwụ ụlọ nke gut.
Deloose et al., 2012 — Nature Reviews GastroenterologyNgwá ọrụ nyocha microbiome nke a họọrọ
Zipu ihe atụ stool. Nkọwa zuru ezu banyere composition bacteria, superfoods nkeonwe, na index inflammation — niile jikọtara na dashboard gị.
16S rRNA + shotgun sequencing, lab-verifiedOlee otú Veliome si arụ ọrụ
Nkeji ise kwa ụbọchị. Nchegharị eziokwu n'ime izu atọ.
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1. Kpọọ onwe gị
Zaa ajụjụ 11 gbasara nri gị, ụra, nrụgide, na mgbaàmà. Veliome na-eme atụmatụ profaịlụ microbiome gị.
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2. Debe
Were foto nri, pịa osisi, debe ferments. App na-eme atụmatụ na na-egosi usoro.
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3. Hazie
Nudge kwa ụbọchị na-egosi gị mgbanwe kachasị elu maka ebe ị malitere. Nnukwu, kpọmkwem, anaghị ekwu okwu.
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4. Soro nsonaazụ
Lee Gut Score gị, mmetụta, na chaatị ike na-agba. Ngwá nyocha nhọrọ na-eme ka ihe oyiyi dị omimi kwa ọnwa isii.
Sayensị dị n'azụ atụmatụ ọ bụla
Veliome bụ nke e wuru na nyocha microbiome nke ndị otu nyocha kwadoro site na afọ iri gara aga. Okwu ọ bụla jikọtara na isi iyi.
Ndụ osisi → ọdịiche microbial
American Gut Project nyochara 11,336 stool samples ma chọpụta na ndị mmadụ na-eri osisi 30+ dị iche iche kwa izu nwere microbiomes gut dị iche iche nke ukwuu — na ọnụ ọgụgụ gene na-emegide ọgwụ antibiotics dị ala — karịa ndị na-eri 10 ma ọ bụ karịa.
McDonald et al., mSystems 2018Foods fermented na-ebelata inflammation
N'ịbụ na 10-izu randomized Stanford trial, ndị okenye dị mma ndị tinyere 6 servings kwa ụbọchị nke fermented foods na nri ha bulitere ọdịiche microbial NA belatara 19 proteins na-emetụta inflammation, gụnyere IL-6 — nke metụtara ọrịa ogologo oge.
Wastyk et al., Cell 2021Mmetụta biara na gut
Ihe dị ka 95% nke serotonin nke ahụ na-emepụta na enterochromaffin cells na-ehicha afọ. Bacteria ụfọdụ (spore-forming, gụnyere Clostridium na Turicibacter) na-achịkwa biosynthesis ya ozugbo. Vagus nerve na-ebufe ihe ngosi afọ na ụbụrụ n'ime nkeji.
Yano et al., Cell 2015 · Cryan et al., Physiological Reviews 2019Ultra-processed food (UPF) na afọ
UPFs na-ebelata microbial diversity, na-akpata inflammation, na-emegide satiety. Ha ugbu a na-eme ~58% nke calories na US na 60% na UK. Ịṅụ UPF dị elu na-ejikọta onwe ya na ọnwụ n'ihi ihe niile na nnukwu cohorts na-atụ anya.
Monteiro et al., 2019 · Pagliai et al., 2021Oral microbes na-emetụta ụbụrụ
Porphyromonas gingivalis, bacteria nke na-eme ka chronic periodontitis, achọpụtara na ụbụrụ Alzheimer na CSF. Ịsacha ọnụ kwa ụbọchị na-elekọta asụsụ na-ebelata oral pathogen load na systemic inflammation.
Dominy et al., Science Advances 2019Nzaghachi nkeonwe bụ eziokwu
Nnyocha PREDICT-1 (1,098 ndị mmadụ nwere phenotypes dị omimi) gosiri na postprandial glucose, insulin, na triglyceride nzaghachi na nri yiri ya na-agbanwe nke ukwuu n'etiti ndị mmadụ — na microbiome composition bụ otu n'ime ndị na-eme ka mgbanwe ahụ pụta. Nkwupụta nri nkịtị na-ada ụda n'ihi na ọ na-ezighị ezi gị.
Asnicar et al., Nature Medicine 2021Ntụle a họọrọ
- McDonald, D. et al. (2018). American Gut: An Open Platform for Citizen Science Microbiome Research. mSystems, 3(3).
- Wastyk, H. C. et al. (2021). Gut-microbiota-targeted diets modulate human immune status. Cell, 184(16), 4137–4153.
- Cryan, J. F. et al. (2019). The Microbiota-Gut-Brain Axis. Physiological Reviews, 99(4), 1877–2013.
- Monteiro, C. A. et al. (2019). Ultra-processed foods: what they are and how to identify them. Public Health Nutrition, 22(5), 936–941.
- Dominy, S. S. et al. (2019). Porphyromonas gingivalis in Alzheimer's disease brains. Science Advances, 5(1).
- Deloose, E. et al. (2012). The migrating motor complex: control mechanisms and its role in health and disease. Nature Reviews Gastroenterology & Hepatology, 9, 271–285.
- Berding, K. et al. (2023). A specific dietary fibre supplementation improves cognitive performance — an exploratory randomised, placebo-controlled, crossover study. Psychopharmacology.
- Asnicar, F. et al. (2021). Microbiome connections with host metabolism and habitual diet from 1,098 deeply phenotyped individuals. Nature Medicine, 27, 321–332. (PREDICT-1)
- Berding, K. et al. (2021). Diet and the microbiota-gut-brain axis: sowing the seeds of good mental health. Advances in Nutrition, 12(4).
- Sender, R., Fuchs, S., & Milo, R. (2016). Revised estimates for the number of human and bacteria cells in the body. PLoS Biology, 14(8).
- Yano, J. M. et al. (2015). Indigenous bacteria from the gut microbiota regulate host serotonin biosynthesis. Cell, 161(2), 264–276.
- Pase, M. P. et al. (2020). Sleep architecture and the risk of incident dementia in the community. Neurology, 95(5).
- Beilharz, J. E. et al. (2015). Diet-induced cognitive deficits: The role of fat and sugar, potential mechanisms and nutritional interventions. Nutrients, 7(8).
- Sonnenburg, J. L., & Sonnenburg, E. D. (2019). The ancestral and industrialized gut microbiota and implications for human health. Nature Reviews Microbiology, 17, 383–390.
- Valdes, A. M. et al. (2018). Role of the gut microbiota in nutrition and health. BMJ, 361.
Ndị otu na-ahụ ya ugbu a
Enweghị m echiche na ụdị dị mkpa karịa ọnụọgụ. 30-plant tracker gbanwere ihe niile. E si m na 8 osisi n'izu gaa na 34 n'ime izu atọ — na n'ikpeazụ kwụsịrị na 9am.
Chaatị mmekọrịta mmetụta-nri bụ ihe mepere emepe. E kwusịrị m ịlụso mgbatị ehihie ọgụ, ma malite ịkwụsị ya.
Dọkịta m na-ahụ maka afọ jụrụ m ihe m gbanwere. E gosiri m ya eserese Gut Score. O wepụtara ngwa ahụ n'ehihie ahụ.
Ajụjụ a na-ajụkarị
Ọ bụ Veliome ngwaọrụ ọgwụ ma ọ bụ ngwá ọrụ nyocha?
Mba. Veliome bụ ngwa wellness e mere iji mee ka nchọpụta microbiome bụrụ ihe a na-eme. Ọ naghị achọpụta, ọgwụgwọ, gwọọ, ma ọ bụ gbochie ọrịa ọ bụla. Maka ọnọdụ ọgwụ, jụọ dọkịta.
Ị chọrọ kit nyocha iji jiri ngwa ahụ?
Mba. Ngalaba efu na nke a na-akwụ ụgwọ na-arụ ọrụ na-enweghị nyocha ụlọ. Kit ahụ bụ mgbakwunye nhọrọ nke na-enye profaịlụ bakteria nkeonwe na ndepụta nri nkeonwe.
Kedu ndị ọkà mmụta sayensị mere ka Veliome bụrụ ihe?
Ngwa ahụ nwere nnukwu ozi sitere na Prof. Tim Spector (King's College London / ZOE / PREDICT), Justin Sonnenburg (Stanford), John Cryan (APC Microbiome Ireland), na nnukwu otu American Gut Project. A na-ejikọta nkwupụta niile na isi mmalite ndị a na-enyocha.
Kedu ka nkwado asụsụ 108 si arụ ọrụ?
Ma ngwa ahụ na weebụsaịtị a na-atụgharị site na iji OpenAI's gpt-4o-mini model. Weebụsaịtị ahụ na-emegharị otu ibe HTML kwa asụsụ maka indexing zuru ezu nke injin nchọgharị.
Ọ bụ data m nzuzo?
Ee. A na-echekwa ndekọ nri niile, ntinye mmetụta, na metrics na ngwaọrụ gị site na ndabara. Enweghị data nkeonwe na-apụ na ekwentị gị ma ọ bụrụ na ị kwadoro nke ọma ịbanye na panel nchọpụta.
Ọ ga-arụ ọrụ Veliome ma ọ bụrụ na m bụ vegan / keto / Mediterranean?
Ee. Veliome bụ nke na-adịghị atụgharị na ụdị nri. Usoro 30-plants na nduzi nri fermented na-eme ka ụdị nri ọ bụla dịkwuo mma.
Kedu ka nke a si dị iche na MyFitnessPal ma ọ bụ Yuka?
MyFitnessPal na-achọpụta kalori. Yuka na-enyocha ngwaahịa na ụlọ ahịa. Veliome bụ nke e mere maka sayensị microbiome: ọdịiche, ferments, UPF ibu, na axis gut-brain — ọ bụghị ịgụ kalori.
Ebee ka m ga-agụ ọmụmụ ndị ahụ?
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Malite njem microbiome gị taa
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